Corticosterone release in oxytocin gene deletion mice following exposure to psychogenic versus non-psychogenic stress

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Enhanced corticosterone concentrations and attenuated Fos expression in the medial amygdala of female oxytocin knockout mice exposed to psychogenic stress.

Centrally released oxytocin (OT) is believed to attenuate the response of the hypothalamic-pituitary-adrenal (HPA) axis to psychogenic stress. To test this hypothesis, we measured plasma corticosterone concentrations and Fos-immunoreactive protein in the paraventricular nucleus of the hypothalamus (PVN) and limbic brain areas of female wild-type and OT knockout mice that were exposed to a shake...

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ژورنال

عنوان ژورنال: Neuroscience Letters

سال: 2008

ISSN: 0304-3940

DOI: 10.1016/j.neulet.2008.07.004